Cargando…

Therapeutic effects of calcium dobesilate on diabetic nephropathy mediated through reduction of expression of PAI-1

The aim of this study was to investigate whether calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) may be used to treat diabetic nephropathy. A total of 121 patients with type 2 diabetic nephropathy received calcium dobesilate (500 mg, 3 times a day) for 3 months. The levels of glycated he...

Descripción completa

Detalles Bibliográficos
Autor principal:	ZHANG, XIAOQIAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524077/ https://www.ncbi.nlm.nih.gov/pubmed/23251286 http://dx.doi.org/10.3892/etm.2012.755

Ejemplares similares

Combined treatment of diabetic nephropathy with alprostadil and calcium dobesilate
por: Qin, Lili, et al.
Publicado: (2017)

Effect of Calcium Dobesilate in Preventing Contrast-Induced Nephropathy in Patients with Diabetes and Chronic Kidney Disease
por: Zhang, Hao, et al.
Publicado: (2021)

Mechanisms of retinal neuroprotection of calcium dobesilate: therapeutic implications
por: Simó-Servat, Olga, et al.
Publicado: (2017)

Calcium dobesilate may alleviate diabetes-induced endothelial dysfunction and inflammation
por: Zhou, Yijun, et al.
Publicado: (2017)

Molecular Mechanisms and Treatment Strategies in Diabetic Nephropathy: New Avenues for Calcium Dobesilate—Free Radical Scavenger and Growth Factor Inhibition
por: Haller, Hermann, et al.
Publicado: (2017)

Calcium dobesilate-induced hyperpyrexia: A case report
por: Yang, Hui, et al.
Publicado: (2023)

Can calcium dobesilate be used safely for peripheral microvasculopathies that require neoangiogenesis?
por: Demirtas, Sinan, et al.
Publicado: (2013)

Selected Physicochemical Properties of Lyophilized Hydrogel with Liposomal Fraction of Calcium Dobesilate
por: Pilch, Ewa, et al.
Publicado: (2018)

Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice
por: Hakimizadeh, Elham, et al.
Publicado: (2022)

Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose
por: Zhou, Yijun, et al.
Publicado: (2019)

Calcium dobesilate reduces endothelin-1 and high-sensitivity C-reactive protein serum levels in patients with diabetic retinopathy
por: Javadzadeh, Alireza, et al.
Publicado: (2013)

Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes
por: Leal, Ermelindo C., et al.
Publicado: (2010)

Modulation of the intramedullary pressure responses by calcium dobesilate in a rabbit knee model of osteoarthritis
por: Miles, James E, et al.
Publicado: (2011)

Calcium dobesilate efficiency in the treatment of diabetic kidney disease through suppressing MAPK and chemokine signaling pathways based on clinical evaluation and network pharmacology
por: Du, Bingyu, et al.
Publicado: (2022)

Effects of calcium dobesilate on Nrf2, Keap1 and HO-1 in the lenses of D-galactose-induced cataracts in rats
por: Sun, Jinfeng, et al.
Publicado: (2018)

Calcium Dobesilate Versus Flavonoids for the Treatment of Early Hemorrhoidal Disease: A Randomized Controlled Trial
por: Changazi, Shabbar H, et al.
Publicado: (2020)

A new method for anti‐negative interference of calcium dobesilate in serum creatinine enzymatic analysis
por: Shen, Hailan, et al.
Publicado: (2021)

Simultaneous estimation of troxerutin and calcium dobesilate in presence of the carcinogenic hydroquinone using green spectrofluorimetric method
por: Tolba, M. M., et al.
Publicado: (2021)

Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice
por: Njau, Florence, et al.
Publicado: (2020)

Strong Negative Interference by Calcium Dobesilate in Sarcosine Oxidase Assays for Serum Creatinine Involving the Trinder Reaction
por: Guo, Xiuzhi, et al.
Publicado: (2015)

Negative interferences by calcium dobesilate in the detection of five serum analytes involving Trinder reaction-based assays
por: Guo, Xiuzhi, et al.
Publicado: (2018)

Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes
por: Deng, Jianxin, et al.
Publicado: (2021)

Correction: Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice
por: Njau, Florence, et al.
Publicado: (2020)

Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway
por: Wang, Yue, et al.
Publicado: (2019)

PAI-1 in Diabetes: Pathophysiology and Role as a Therapeutic Target
por: Altalhi, Rawan, et al.
Publicado: (2021)

Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress
por: Hakimizadeh, Elham, et al.
Publicado: (2021)

Short-term efficacy of intravitreal dobesilate in central serous chorioretinopathy
por: Cuevas, Pedro, et al.
Publicado: (2012)

Dramatic resolution of vitreous hemorrhage after an intravitreal injection of dobesilate
por: Cuevas, Pedro, et al.
Publicado: (2015)

Intravitreal Ranibizumab Alone or in Combination with Calcium Dobesilate for the Treatment of Diabetic Macular Edema in Nonproliferative Diabetic Retinopathy Patients: 12-Month Outcomes of a Retrospective Study
por: Wang, Dongxuan, et al.
Publicado: (2022)

Calcium dobesilate reduces SARS-CoV-2 entry into endothelial cells by inhibiting virus binding to heparan sulfate
por: Kiyan, Yulia, et al.
Publicado: (2022)

Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops
por: Cuevas, Pedro, et al.
Publicado: (2015)

Effect of Chinese Patent Medicines on Ocular Fundus Signs and Vision in Calcium Dobesilate-Treated Persons With Non-Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis
por: Zhang, Yuehong, et al.
Publicado: (2022)

Author Correction: Calcium dobesilate reduces SARS-CoV-2 entry into endothelial cells by inhibiting virus binding to heparan sulfate
por: Kiyan, Yulia, et al.
Publicado: (2023)

Dobesilate diminishes activation of the mitogen - activated protein kinase ERK1/2 in glioma cells
por: Cuevas, P, et al.
Publicado: (2006)

Effects of teneligliptin on PDMPs and PAI-1 in patients with diabetes on hemodialysis
por: Okuda, Yoshinori, et al.
Publicado: (2016)

A Drug–Drug Multicomponent Crystal of Metformin and Dobesilate: Crystal Structure Analysis and Hygroscopicity Property
por: Jiang, Lan, et al.
Publicado: (2022)

Calcium dobesilate alleviates renal dysfunction and inflammation by targeting nuclear factor kappa B (NF-κB) signaling in sepsis-associated acute kidney injury
por: Xie, Zhijuan, et al.
Publicado: (2022)

Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis
por: Njau, Florence, et al.
Publicado: (2021)

Efficacy of calcium dobesilate in treating Chinese patients with mild-to-moderate non-proliferative diabetic retinopathy (CALM-DR): protocol for a single-blind, multicentre, 24-armed cluster-randomised, controlled trial
por: Hu, Hao, et al.
Publicado: (2021)

Topical treatment of actinic keratoses with potassium dobesilate 5% cream. A preliminary open-label study
por: Cuevas, P, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_p8a29uvauh603kbugs2ts4c3cp