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Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus

Visual neurons have spatial receptive fields that encode the positions of objects relative to the fovea. Because foveate animals execute frequent saccadic eye movements, this position information is constantly changing, even though the visual world is generally stationary. Interestingly, visual rece...

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Detalles Bibliográficos
Autores principales: Churan, Jan, Guitton, Daniel, Pack, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524080/
https://www.ncbi.nlm.nih.gov/pubmed/23284931
http://dx.doi.org/10.1371/journal.pone.0052195
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author Churan, Jan
Guitton, Daniel
Pack, Christopher C.
author_facet Churan, Jan
Guitton, Daniel
Pack, Christopher C.
author_sort Churan, Jan
collection PubMed
description Visual neurons have spatial receptive fields that encode the positions of objects relative to the fovea. Because foveate animals execute frequent saccadic eye movements, this position information is constantly changing, even though the visual world is generally stationary. Interestingly, visual receptive fields in many brain regions have been found to exhibit changes in strength, size, or position around the time of each saccade, and these changes have often been suggested to be involved in the maintenance of perceptual stability. Crucial to the circuitry underlying perisaccadic changes in visual receptive fields is the superior colliculus (SC), a brainstem structure responsible for integrating visual and oculomotor signals. In this work we have studied the time-course of receptive field changes in the SC. We find that the distribution of the latencies of SC responses to stimuli placed outside the fixation receptive field is bimodal: The first mode is comprised of early responses that are temporally locked to the onset of the visual probe stimulus and stronger for probes placed closer to the classical receptive field. We suggest that such responses are therefore consistent with a perisaccadic rescaling, or enhancement, of weak visual responses within a fixed spatial receptive field. The second mode is more similar to the remapping that has been reported in the cortex, as responses are time-locked to saccade onset and stronger for stimuli placed in the postsaccadic receptive field location. We suggest that these two temporal phases of spatial updating may represent different sources of input to the SC.
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spelling pubmed-35240802013-01-02 Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus Churan, Jan Guitton, Daniel Pack, Christopher C. PLoS One Research Article Visual neurons have spatial receptive fields that encode the positions of objects relative to the fovea. Because foveate animals execute frequent saccadic eye movements, this position information is constantly changing, even though the visual world is generally stationary. Interestingly, visual receptive fields in many brain regions have been found to exhibit changes in strength, size, or position around the time of each saccade, and these changes have often been suggested to be involved in the maintenance of perceptual stability. Crucial to the circuitry underlying perisaccadic changes in visual receptive fields is the superior colliculus (SC), a brainstem structure responsible for integrating visual and oculomotor signals. In this work we have studied the time-course of receptive field changes in the SC. We find that the distribution of the latencies of SC responses to stimuli placed outside the fixation receptive field is bimodal: The first mode is comprised of early responses that are temporally locked to the onset of the visual probe stimulus and stronger for probes placed closer to the classical receptive field. We suggest that such responses are therefore consistent with a perisaccadic rescaling, or enhancement, of weak visual responses within a fixed spatial receptive field. The second mode is more similar to the remapping that has been reported in the cortex, as responses are time-locked to saccade onset and stronger for stimuli placed in the postsaccadic receptive field location. We suggest that these two temporal phases of spatial updating may represent different sources of input to the SC. Public Library of Science 2012-12-17 /pmc/articles/PMC3524080/ /pubmed/23284931 http://dx.doi.org/10.1371/journal.pone.0052195 Text en © 2012 Churan et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Churan, Jan
Guitton, Daniel
Pack, Christopher C.
Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title_full Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title_fullStr Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title_full_unstemmed Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title_short Perisaccadic Remapping and Rescaling of Visual Responses in Macaque Superior Colliculus
title_sort perisaccadic remapping and rescaling of visual responses in macaque superior colliculus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524080/
https://www.ncbi.nlm.nih.gov/pubmed/23284931
http://dx.doi.org/10.1371/journal.pone.0052195
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