Loss of Atrx Sensitizes Cells to DNA Damaging Agents through p53-Mediated Death Pathways

Prevalent cell death in forebrain- and Sertoli cell-specific Atrx knockout mice suggest that Atrx is important for cell survival. However, conditional ablation in other tissues is not associated with increased death indicating that diverse cell types respond differently to the loss of this chromatin...

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Detalles Bibliográficos
Autores principales: Conte, Damiano, Huh, Michael, Goodall, Emma, Delorme, Marilyne, Parks, Robin J., Picketts, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524112/
https://www.ncbi.nlm.nih.gov/pubmed/23284920
http://dx.doi.org/10.1371/journal.pone.0052167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524112/
https://www.ncbi.nlm.nih.gov/pubmed/23284920
http://dx.doi.org/10.1371/journal.pone.0052167

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