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Epigenetic Changes in Basal Cell Carcinoma Affect SHH and WNT Signaling Components

BACKGROUND: The genetic background of Basal Cell Carcinoma (BCC) has been studied extensively, while its epigenetic makeup has received comparatively little attention. Epigenetic alterations such as promoter hypermethylation silence tumor suppressor genes (TSG) in several malignancies. OBJECTIVE: We...

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Detalles Bibliográficos
Autores principales:	Brinkhuizen, Tjinta, van den Hurk, Karin, Winnepenninckx, Véronique J. L., de Hoon, Joep P., van Marion, Ariënne M., Veeck, Jürgen, van Engeland, Manon, van Steensel, Maurice A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524166/ https://www.ncbi.nlm.nih.gov/pubmed/23284750 http://dx.doi.org/10.1371/journal.pone.0051710

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