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The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages

The unique PE/PPE multigene family of proteins occupies almost 10% of the coding sequence of Mycobacterium tuberculosis (M.tb), the causative agent of human tuberculosis. Although some members of this family have been shown to be involved in pathways essential to M.tb pathogenesis, their precise phy...

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Detalles Bibliográficos
Autores principales: Tiwari, Bhavana Mishra, Kannan, Nisha, Vemu, Lakshmi, Raghunand, Tirumalai R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524191/
https://www.ncbi.nlm.nih.gov/pubmed/23284742
http://dx.doi.org/10.1371/journal.pone.0051686