Disulfide Bonds within the C2 Domain of RAGE Play Key Roles in Its Dimerization and Biogenesis

BACKGROUND: The receptor for advanced glycation end products (RAGE) on the cell surface transmits inflammatory signals. A member of the immunoglobulin superfamily, RAGE possesses the V, C1, and C2 ectodomains that collectively constitute the receptor's extracellular structure. However, the mole...

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Detalles Bibliográficos
Autores principales: Wei, Wen, Lampe, Leonie, Park, Sungha, Vangara, Bhavana S., Waldo, Geoffrey S., Cabantous, Stephanie, Subaran, Sarah S., Yang, Dongmei, Lakatta, Edward G., Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524233/
https://www.ncbi.nlm.nih.gov/pubmed/23284645
http://dx.doi.org/10.1371/journal.pone.0050736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524233/
https://www.ncbi.nlm.nih.gov/pubmed/23284645
http://dx.doi.org/10.1371/journal.pone.0050736

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