The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-e cells through RhoA/TGFβ1/SFK pathway

BACKGROUND: Osteogenic growth peptide (OGP) is a 14-mer peptide found in relevant concentration in blood, and its carboxy-terminal fragment [OGP(10-14)] represents the active portion of the full-length peptide. In addition to stimulating bone formation, OGP(10-14) shows hematological activity. In fa...

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Detalles Bibliográficos
Autores principales: Battolla, Barbara, Bernardini, Nunzia, Petrini, Mario, Mattii, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524689/
https://www.ncbi.nlm.nih.gov/pubmed/21169922
http://dx.doi.org/10.12659/MSM.881309

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