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Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
BACKGROUND: Sigma receptors are highly expressed in human tumors and should be appropriate targets for developing tumor imaging agents. Previously, we synthesized a vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino]cyclohexanol ((+)-pIV), with a high affinity for sigma receptors and prepared radio...
Autores principales: | Ogawa, Kazuma, Kanbara, Hiroya, Shiba, Kazuhiro, Kitamura, Yoji, Kozaka, Takashi, Kiwada, Tatsuto, Odani, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524758/ https://www.ncbi.nlm.nih.gov/pubmed/23021206 http://dx.doi.org/10.1186/2191-219X-2-54 |
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