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How does doxorubicin work?

A new mechanism involving cleavage of a transcription factor called CREB3L1 has been proposed to explain the anti-tumour effects of doxorubicin.

Detalles Bibliográficos
Autores principales: Patel, Anand G, Kaufmann, Scott H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524826/
https://www.ncbi.nlm.nih.gov/pubmed/23256047
http://dx.doi.org/10.7554/eLife.00387
Descripción
Sumario:A new mechanism involving cleavage of a transcription factor called CREB3L1 has been proposed to explain the anti-tumour effects of doxorubicin.