KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polycomb response elements (PREs) and are recognized by the polycomb silencing systems to regulate expression of genes involved in early development. How CGIs function mechanistically as nucleation sites fo...

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Detalles Bibliográficos
Autores principales: Farcas, Anca M, Blackledge, Neil P, Sudbery, Ian, Long, Hannah K, McGouran, Joanna F, Rose, Nathan R, Lee, Sheena, Sims, David, Cerase, Andrea, Sheahan, Thomas W, Koseki, Haruhiko, Brockdorff, Neil, Ponting, Chris P, Kessler, Benedikt M, Klose, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524939/
https://www.ncbi.nlm.nih.gov/pubmed/23256043
http://dx.doi.org/10.7554/eLife.00205

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