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Activation of PAD4 in NET formation

Peptidylarginine deiminases, or PADs, convert arginine residues to the non-ribosomally encoded amino acid citrulline in a variety of protein substrates. PAD4 is expressed in granulocytes and is essential for the formation of neutrophil extracellular traps (NETs) via PAD4-mediated histone citrullinat...

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Detalles Bibliográficos
Autores principales:	Rohrbach, Amanda S., Slade, Daniel J., Thompson, Paul R., Mowen, Kerri A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525017/ https://www.ncbi.nlm.nih.gov/pubmed/23264775 http://dx.doi.org/10.3389/fimmu.2012.00360

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