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Trick or treat: The effect of placebo on the power of pharmacogenetic association studies

The genetic mapping of drug-response traits is often characterised by a poor signal-to-noise ratio that is placebo related and which distinguishes pharmacogenetic association studies from classical case-control studies for disease susceptibility. The goal of this study was to evaluate the statistica...

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Detalles Bibliográficos
Autores principales: Singer, Clara, Grossman, Iris, Avidan, Nili, Beckmann, Jacques S, Pe'er, Itsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525118/
https://www.ncbi.nlm.nih.gov/pubmed/15814066
http://dx.doi.org/10.1186/1479-7364-2-1-28