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From DNA to RNA to disease and back: The 'central dogma' of regulatory disease variation

Much of the focus of human disease genetics is directed towards identifying nucleotide variants that contribute to disease phenotypes. This is a complex problem, often involving contributions from multiple loci and their interactions, as well as effects due to environmental factors. Although some di...

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Detalles Bibliográficos
Autores principales: Stranger, Barbara E, Dermitzakis, Emmanouil T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525162/
https://www.ncbi.nlm.nih.gov/pubmed/16848976
http://dx.doi.org/10.1186/1479-7364-2-6-383

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