A high incidence of polymorphic CYP2C19 variants in archival blood samples from Papua New Guinea

There is considerable inter-ethnic variability in the incidence of CYP2C19 genetic poor metabolisers (var/var). About 3 per cent of Caucasians are CYP2C19 var/var. By contrast, an extremely high incidence (70 per cent) is observed in the Melanesian island of Vanuatu. The colonisation of the Pacific...

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Detalles Bibliográficos
Autores principales: Hsu, Huai-Ling, Woad, Kathryn J, Woodfield, D Graeme, Helsby, Nuala A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525181/
https://www.ncbi.nlm.nih.gov/pubmed/19129087
http://dx.doi.org/10.1186/1479-7364-3-1-17

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