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Mitochondrial DNA sequence variation and neurodegeneration

Mitochondria, the powerhouse of the cell, play a critical role in several metabolic processes and apoptotic pathways. Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. Moreover, there is a long history of investigations on mitochondria...

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Detalles Bibliográficos
Autores principales: Mancuso, Michelangelo, Filosto, Massimiliano, Orsucci, Daniele, Siciliano, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525185/
https://www.ncbi.nlm.nih.gov/pubmed/19129091
http://dx.doi.org/10.1186/1479-7364-3-1-71