Cargando…
The genetics of regulatory variation in the human genome
The regulation of gene expression plays an important role in complex phenotypes, including disease in humans. For some genes, the genetic mechanisms influencing gene expression are well elucidated; however, it is unclear how applicable these results are to gene expression on a genome-wide level. Stu...
Autores principales: | Stranger, Barbara E, Dermitzakis, Emmanouil T |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525257/ https://www.ncbi.nlm.nih.gov/pubmed/16004727 http://dx.doi.org/10.1186/1479-7364-2-2-126 |
Ejemplares similares
-
From DNA to RNA to disease and back: The 'central dogma' of regulatory disease variation
por: Stranger, Barbara E, et al.
Publicado: (2006) -
Modifier Effects between Regulatory and Protein-Coding Variation
por: Dimas, Antigone S., et al.
Publicado: (2008) -
Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations
por: Nica, Alexandra C., et al.
Publicado: (2010) -
Gene Expression Levels Are a Target of Recent Natural Selection in the Human Genome
por: Kudaravalli, Sridhar, et al.
Publicado: (2009) -
Rare and Common Regulatory Variation in Population-Scale Sequenced Human Genomes
por: Montgomery, Stephen B., et al.
Publicado: (2011)