Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

Pharmacogenetics enables personalised therapy based on genetic profiling and is increasingly applied in drug discovery. Medicines are developed and used together with pharmacodiagnostic tools to achieve desired drug efficacy and safety margins. Genetic polymorphism of drug-metabolising enzymes such...

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Detalles Bibliográficos
Autores principales: Matimba, Alice, Del-Favero, Jurgen, Van Broeckhoven, Christine, Masimirembwa, Collen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525272/
https://www.ncbi.nlm.nih.gov/pubmed/19164093
http://dx.doi.org/10.1186/1479-7364-3-2-169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525272/
https://www.ncbi.nlm.nih.gov/pubmed/19164093
http://dx.doi.org/10.1186/1479-7364-3-2-169

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