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Antibody Fragments Directed against Different Portions of the Human Neural Cell Adhesion Molecule L1 Act as Inhibitors or Activators of L1 Function

The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the metastatic potential of tumors. To select antibodies t...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Loers, Gabriele, Pan, Hong-Chao, Gouveia, Ricardo, Zhao, Wei-Jiang, Shen, Yan-Qin, Kleene, Ralf, Costa, Julia, Schachner, Melitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525558/
https://www.ncbi.nlm.nih.gov/pubmed/23272240
http://dx.doi.org/10.1371/journal.pone.0052404