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Antibody Fragments Directed against Different Portions of the Human Neural Cell Adhesion Molecule L1 Act as Inhibitors or Activators of L1 Function
The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the metastatic potential of tumors. To select antibodies t...
Autores principales: | Wang, Yan, Loers, Gabriele, Pan, Hong-Chao, Gouveia, Ricardo, Zhao, Wei-Jiang, Shen, Yan-Qin, Kleene, Ralf, Costa, Julia, Schachner, Melitta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525558/ https://www.ncbi.nlm.nih.gov/pubmed/23272240 http://dx.doi.org/10.1371/journal.pone.0052404 |
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