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The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons
BACKGROUND: Compound 48/80 is widely used in animal and tissue models as a “selective” mast cell activator. With this study we demonstrate that compound 48/80 also directly activates enteric neurons and visceral afferents. METHODOLOGY/PRINCIPAL FINDINGS: We used in vivo recordings from extrinsic int...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525567/ https://www.ncbi.nlm.nih.gov/pubmed/23272218 http://dx.doi.org/10.1371/journal.pone.0052104 |