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Sequence Variants of Toll Like Receptor 4 and Late-Onset Alzheimer's Disease

BACKGROUND: Toll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain. No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD risk previously and ApoE e4 status alon...

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Detalles Bibliográficos
Autores principales:	Chen, Yen-Ching, Yip, Ping-Keung, Huang, Yi-Ling, Sun, Yu, Wen, Li-Li, Chu, Yi-Min, Chen, Ta-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525588/ https://www.ncbi.nlm.nih.gov/pubmed/23272070 http://dx.doi.org/10.1371/journal.pone.0050771

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