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Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice

BACKGROUND: Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility gene for schizophrenia and other psychiatric disorders. Disc1-L100P mutant mice show behaviors relevant to schizophrenia at 12 weeks, but not at 8 weeks...

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Detalles Bibliográficos
Autores principales:	Lipina, Tatiana V., Haque, Fahmida Nipa, McGirr, Alexander, Boutros, Paul C., Berger, Thorsten, Mak, Tak W., Roder, John C., Wong, Albert H. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525594/ https://www.ncbi.nlm.nih.gov/pubmed/23272119 http://dx.doi.org/10.1371/journal.pone.0051562

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