Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction

Myeloid-derived suppressor cells (MDSCs), identified as Gr1(+)CD11b(+) cells in mice, expand during cancer and promote tumor growth, recurrence and burden. However, little is known about their role in bone metastases. We hypothesized that MDSCs may contribute to tumor-induced bone disease, and inocu...

Descripción completa

Detalles Bibliográficos
Autores principales: Danilin, Sabrina, Merkel, Alyssa R., Johnson, Joshua R., Johnson, Rachelle W., Edwards, James R., Sterling, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525604/
https://www.ncbi.nlm.nih.gov/pubmed/23264895
http://dx.doi.org/10.4161/onci.21990

Ejemplares similares

Ejemplares similares