Inefficient boosting of antitumor CD8(+) T cells by dendritic-cell vaccines is rescued by restricting T-cell cytotoxic functions

Dendritic cells (DCs) are powerful activators of primary and secondary immune responses and have promising activity as anticancer vaccines. However, various populations of immune cells, including natural killer cells, regulatory T cells and especially cytotoxic T lymphocytes (CTLs), can inhibit DC f...

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Detalles Bibliográficos
Autores principales: Zhi-Iong Ma, Joel, Yang, Jianping, Qin, Jim S., Richter, Antonia, Perret, Rachel, El-Deiry, Wafik S., Finnberg, Niklas, ronchese, franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525606/
https://www.ncbi.nlm.nih.gov/pubmed/23264897
http://dx.doi.org/10.4161/onci.22128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525606/
https://www.ncbi.nlm.nih.gov/pubmed/23264897
http://dx.doi.org/10.4161/onci.22128

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