Modulating CD27 signaling to treat cancer

CD27 signaling can either improve T-cell function or lead to T-cell dysfunction, depending on the duration and conditions of receptor ligation. Recent studies have shown that modulating the CD70-CD27 interaction is an attractive strategy to treat solid tumors and also to directly target leukemia ste...

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Detalles Bibliográficos
Autores principales: Riether, Carsten, Schürch, Christian, Ochsenbein, Adrian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525617/
https://www.ncbi.nlm.nih.gov/pubmed/23264908
http://dx.doi.org/10.4161/onci.21425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525617/
https://www.ncbi.nlm.nih.gov/pubmed/23264908
http://dx.doi.org/10.4161/onci.21425

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