Melanoma immunoediting by NK cells

The immune system can control the early steps of tumor growth, but it may also induce phenotypic/functional changes of malignant cells during tumor progression, favoring immunoescape mechanisms. In a recent study, we revealed how natural killer (NK) cells can participate in such an immunoediting pro...

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Autores principales: Balsamo, Mirna, Pietra, Gabriella, Vermi, William, Moretta, Lorenzo, Mingari, Maria Cristina, Vitale, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525618/
https://www.ncbi.nlm.nih.gov/pubmed/23264909
http://dx.doi.org/10.4161/onci.21456
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author Balsamo, Mirna
Pietra, Gabriella
Vermi, William
Moretta, Lorenzo
Mingari, Maria Cristina
Vitale, Massimo
author_facet Balsamo, Mirna
Pietra, Gabriella
Vermi, William
Moretta, Lorenzo
Mingari, Maria Cristina
Vitale, Massimo
author_sort Balsamo, Mirna
collection PubMed
description The immune system can control the early steps of tumor growth, but it may also induce phenotypic/functional changes of malignant cells during tumor progression, favoring immunoescape mechanisms. In a recent study, we revealed how natural killer (NK) cells can participate in such an immunoediting process, by rendering melanoma cells resistant to NK-mediated killing.
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spelling pubmed-35256182012-12-21 Melanoma immunoediting by NK cells Balsamo, Mirna Pietra, Gabriella Vermi, William Moretta, Lorenzo Mingari, Maria Cristina Vitale, Massimo Oncoimmunology Author's View The immune system can control the early steps of tumor growth, but it may also induce phenotypic/functional changes of malignant cells during tumor progression, favoring immunoescape mechanisms. In a recent study, we revealed how natural killer (NK) cells can participate in such an immunoediting process, by rendering melanoma cells resistant to NK-mediated killing. Landes Bioscience 2012-12-01 /pmc/articles/PMC3525618/ /pubmed/23264909 http://dx.doi.org/10.4161/onci.21456 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Balsamo, Mirna
Pietra, Gabriella
Vermi, William
Moretta, Lorenzo
Mingari, Maria Cristina
Vitale, Massimo
Melanoma immunoediting by NK cells
title Melanoma immunoediting by NK cells
title_full Melanoma immunoediting by NK cells
title_fullStr Melanoma immunoediting by NK cells
title_full_unstemmed Melanoma immunoediting by NK cells
title_short Melanoma immunoediting by NK cells
title_sort melanoma immunoediting by nk cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525618/
https://www.ncbi.nlm.nih.gov/pubmed/23264909
http://dx.doi.org/10.4161/onci.21456
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AT vitalemassimo melanomaimmunoeditingbynkcells

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