Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?

Insights into antitumor T-cell responses may help the development of more efficient treatments for lung cancer. The interplay between preexisting antitumor CD4(+) T-cell responses and platinum-based chemotherapy is crucial to improve patient survival. Accumulating evidence confirms that selecting ca...

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Detalles Bibliográficos
Autores principales: Godet, Yann, Dosset, Magalie, Borg, Christophe, Adotevi, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525622/
https://www.ncbi.nlm.nih.gov/pubmed/23264913
http://dx.doi.org/10.4161/onci.21513
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author Godet, Yann
Dosset, Magalie
Borg, Christophe
Adotevi, Olivier
author_facet Godet, Yann
Dosset, Magalie
Borg, Christophe
Adotevi, Olivier
author_sort Godet, Yann
collection PubMed
description Insights into antitumor T-cell responses may help the development of more efficient treatments for lung cancer. The interplay between preexisting antitumor CD4(+) T-cell responses and platinum-based chemotherapy is crucial to improve patient survival. Accumulating evidence confirms that selecting cancer patients in whom chemotherapy can activate an anticancer immune response would largely improve the success of novel therapeutic approaches.
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spelling pubmed-35256222012-12-21 Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer? Godet, Yann Dosset, Magalie Borg, Christophe Adotevi, Olivier Oncoimmunology Author's View Insights into antitumor T-cell responses may help the development of more efficient treatments for lung cancer. The interplay between preexisting antitumor CD4(+) T-cell responses and platinum-based chemotherapy is crucial to improve patient survival. Accumulating evidence confirms that selecting cancer patients in whom chemotherapy can activate an anticancer immune response would largely improve the success of novel therapeutic approaches. Landes Bioscience 2012-12-01 /pmc/articles/PMC3525622/ /pubmed/23264913 http://dx.doi.org/10.4161/onci.21513 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Godet, Yann
Dosset, Magalie
Borg, Christophe
Adotevi, Olivier
Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title_full Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title_fullStr Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title_full_unstemmed Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title_short Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?
title_sort is preexisting antitumor cd4 t cell response indispensable for the chemotherapy induced immune regression of cancer?
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525622/
https://www.ncbi.nlm.nih.gov/pubmed/23264913
http://dx.doi.org/10.4161/onci.21513
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