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High-quality and high-avidity T cell clones specific for tumor-associated antigens and how to find them
The adoptive transfer of lymphocytes expressing high-avidity T-cell receptors with antitumor specificity provides a promising therapy for cancer patients. Recently, we compared 12 HLA-A2-restricted, tyrosinase peptide-specific CD8(+) cytotoxic T-lymphocyte (CTL) clones and demonstrated that polyfunc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525631/ https://www.ncbi.nlm.nih.gov/pubmed/23264922 http://dx.doi.org/10.4161/onci.21717 |