Emerging evidence of anti-tumor immune control in the central nervous system

Microarray-based studies by our laboratory confirm that the immune control of tumor progression extends to the “immunoprivileged” central nervous system, identifying prognostic immune gene signatures in primary tumor specimens. Our results provide rationale and mechanistic insights for the developme...

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Detalles Bibliográficos
Autores principales: Donson, Andrew M., Foreman, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525633/
https://www.ncbi.nlm.nih.gov/pubmed/23264924
http://dx.doi.org/10.4161/onci.21747
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author Donson, Andrew M.
Foreman, Nicholas K.
author_facet Donson, Andrew M.
Foreman, Nicholas K.
author_sort Donson, Andrew M.
collection PubMed
description Microarray-based studies by our laboratory confirm that the immune control of tumor progression extends to the “immunoprivileged” central nervous system, identifying prognostic immune gene signatures in primary tumor specimens. Our results provide rationale and mechanistic insights for the development of immunotherapeutic strategies against brain tumors.
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spelling pubmed-35256332012-12-21 Emerging evidence of anti-tumor immune control in the central nervous system Donson, Andrew M. Foreman, Nicholas K. Oncoimmunology Author's View Microarray-based studies by our laboratory confirm that the immune control of tumor progression extends to the “immunoprivileged” central nervous system, identifying prognostic immune gene signatures in primary tumor specimens. Our results provide rationale and mechanistic insights for the development of immunotherapeutic strategies against brain tumors. Landes Bioscience 2012-12-01 /pmc/articles/PMC3525633/ /pubmed/23264924 http://dx.doi.org/10.4161/onci.21747 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Donson, Andrew M.
Foreman, Nicholas K.
Emerging evidence of anti-tumor immune control in the central nervous system
title Emerging evidence of anti-tumor immune control in the central nervous system
title_full Emerging evidence of anti-tumor immune control in the central nervous system
title_fullStr Emerging evidence of anti-tumor immune control in the central nervous system
title_full_unstemmed Emerging evidence of anti-tumor immune control in the central nervous system
title_short Emerging evidence of anti-tumor immune control in the central nervous system
title_sort emerging evidence of anti-tumor immune control in the central nervous system
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525633/
https://www.ncbi.nlm.nih.gov/pubmed/23264924
http://dx.doi.org/10.4161/onci.21747
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