Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses

Following activation, γδ T cells display many properties of lymphocytes from the innate immune system, yet how they mediate antigen presentation remains an open conundrum. In humans, circulating γδ T cells that express the Vγ9Vδ2 T-cell receptor become reversibly licensed for professional antigen pr...

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Autores principales: Anderson, John, Gustafsson, Kenth, Himoudi, Nourredine, Yan, Mengyong, Heuijerjans, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525635/
https://www.ncbi.nlm.nih.gov/pubmed/23264926
http://dx.doi.org/10.4161/onci.21971
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author Anderson, John
Gustafsson, Kenth
Himoudi, Nourredine
Yan, Mengyong
Heuijerjans, Jennifer
author_facet Anderson, John
Gustafsson, Kenth
Himoudi, Nourredine
Yan, Mengyong
Heuijerjans, Jennifer
author_sort Anderson, John
collection PubMed
description Following activation, γδ T cells display many properties of lymphocytes from the innate immune system, yet how they mediate antigen presentation remains an open conundrum. In humans, circulating γδ T cells that express the Vγ9Vδ2 T-cell receptor become reversibly licensed for professional antigen presentation only upon interaction with a target cell opsonized with IgGs.
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spelling pubmed-35256352012-12-21 Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses Anderson, John Gustafsson, Kenth Himoudi, Nourredine Yan, Mengyong Heuijerjans, Jennifer Oncoimmunology Author's View Following activation, γδ T cells display many properties of lymphocytes from the innate immune system, yet how they mediate antigen presentation remains an open conundrum. In humans, circulating γδ T cells that express the Vγ9Vδ2 T-cell receptor become reversibly licensed for professional antigen presentation only upon interaction with a target cell opsonized with IgGs. Landes Bioscience 2012-12-01 /pmc/articles/PMC3525635/ /pubmed/23264926 http://dx.doi.org/10.4161/onci.21971 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Anderson, John
Gustafsson, Kenth
Himoudi, Nourredine
Yan, Mengyong
Heuijerjans, Jennifer
Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title_full Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title_fullStr Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title_full_unstemmed Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title_short Licensing of γδT cells for professional antigen presentation: A new role for antibodies in regulation of antitumor immune responses
title_sort licensing of γδt cells for professional antigen presentation: a new role for antibodies in regulation of antitumor immune responses
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525635/
https://www.ncbi.nlm.nih.gov/pubmed/23264926
http://dx.doi.org/10.4161/onci.21971
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