BMP- specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis, and metastasis. However, the mechanism by which it is upregu...

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Detalles Bibliográficos
Autores principales: Tripurani, Swamy K., Cook, Robert W., Eldin, Karen W., Pangas, Stephanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525720/
https://www.ncbi.nlm.nih.gov/pubmed/22964636
http://dx.doi.org/10.1038/onc.2012.392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525720/
https://www.ncbi.nlm.nih.gov/pubmed/22964636
http://dx.doi.org/10.1038/onc.2012.392

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