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Mitophagy in neurodegeneration and aging

Macroautophagy is a cellular catabolic process that involves the sequestration of cytoplasmic constituents into double-membrane vesicles known as autophagosomes, which subsequently fuse with lysosomes, where they deliver their cargo for degradation. The main physiological role of autophagy is to rec...

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Detalles Bibliográficos
Autores principales: Palikaras, Konstantinos, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525948/
https://www.ncbi.nlm.nih.gov/pubmed/23267366
http://dx.doi.org/10.3389/fgene.2012.00297