Cargando…
Computational design of host transcription-factors sets whose misregulation mimics the transcriptomic effect of viral infections
The molecular mechanisms underlying viral pathogenesis are yet poorly understood owed to the large number of factors involved and the complexity of their interactions. Could we identify a minimal set of host transcription factors (TF) whose misregulation would result in the transcriptional profile c...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525979/ https://www.ncbi.nlm.nih.gov/pubmed/23256040 http://dx.doi.org/10.1038/srep01006 |