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Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes
Currently, there is no ideal noninvasive method to quantify the progressive loss of pancreatic β-cell mass (BCM) that occurs in type 1 diabetes. Magnetic resonance imaging has detected gross differences in BCM between healthy and diabetic mice using the contrast agent manganese, which labels functio...
Autores principales: | Antkowiak, Patrick F., Stevens, Brian K., Nunemaker, Craig S., McDuffie, Marcia, Epstein, Frederick H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526033/ https://www.ncbi.nlm.nih.gov/pubmed/22933107 http://dx.doi.org/10.2337/db12-0153 |
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