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Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

Currently, there is no ideal noninvasive method to quantify the progressive loss of pancreatic β-cell mass (BCM) that occurs in type 1 diabetes. Magnetic resonance imaging has detected gross differences in BCM between healthy and diabetic mice using the contrast agent manganese, which labels functio...

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Detalles Bibliográficos
Autores principales: Antkowiak, Patrick F., Stevens, Brian K., Nunemaker, Craig S., McDuffie, Marcia, Epstein, Frederick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526033/
https://www.ncbi.nlm.nih.gov/pubmed/22933107
http://dx.doi.org/10.2337/db12-0153

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