Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

We previously identified a quantitative trait locus for adiposity, non-insulin-dependent diabetes 5 (Nidd5), on mouse chromosome 2. In the current study, we identified the actual genetic alteration at Nidd5 as a nonsense mutation of the Acvr1c gene encoding activin receptor-like kinase 7 (ALK7), one...

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Detalles Bibliográficos
Autores principales: Yogosawa, Satomi, Mizutani, Shin, Ogawa, Yoshihiro, Izumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526038/
https://www.ncbi.nlm.nih.gov/pubmed/22933117
http://dx.doi.org/10.2337/db12-0295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526038/
https://www.ncbi.nlm.nih.gov/pubmed/22933117
http://dx.doi.org/10.2337/db12-0295

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