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Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models
Retinal vascular leakage, inflammation, and neovascularization (NV) are features of diabetic retinopathy (DR). Fenofibrate, a peroxisome proliferator–activated receptor α (PPARα) agonist, has shown robust protective effects against DR in type 2 diabetic patients, but its effects on DR in type 1 diab...
Autores principales: | Chen, Ying, Hu, Yang, Lin, Mingkai, Jenkins, Alicia J., Keech, Anthony C., Mott, Robert, Lyons, Timothy J., Ma, Jian-xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526044/ https://www.ncbi.nlm.nih.gov/pubmed/23043158 http://dx.doi.org/10.2337/db11-0413 |
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