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Computational Design of an α-Gliadin Peptidase

[Image: see text] The ability to rationally modify enzymes to perform novel chemical transformations is essential for the rapid production of next-generation protein therapeutics. Here we describe the use of chemical principles to identify a naturally occurring acid-active peptidase, and the subsequ...

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Detalles Bibliográficos
Autores principales:	Gordon, Sydney R., Stanley, Elizabeth J., Wolf, Sarah, Toland, Angus, Wu, Sean J., Hadidi, Daniel, Mills, Jeremy H., Baker, David, Pultz, Ingrid Swanson, Siegel, Justin B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2012
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526107/ https://www.ncbi.nlm.nih.gov/pubmed/23153249 http://dx.doi.org/10.1021/ja3094795

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