Cargando…
Anticoagulant therapy for ischemic stroke: A review of literature
For many years, anticoagulants have been used in the emergent treatment of patients with acute ischemic stroke. Anticoagulants are prescribed in an effort to prevent first or recurrent stroke, especially among patients with cardioembolism due to arterial fibrillation and large-artery atherosclerotic...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526137/ https://www.ncbi.nlm.nih.gov/pubmed/23267405 |
_version_ | 1782253511008845824 |
---|---|
author | Shahpouri, Mohammad Mehdi Mousavi, Seyed Khorvash, Faribourz Mousavi, Seyed Morteza Hoseini, Tahereh |
author_facet | Shahpouri, Mohammad Mehdi Mousavi, Seyed Khorvash, Faribourz Mousavi, Seyed Morteza Hoseini, Tahereh |
author_sort | Shahpouri, Mohammad Mehdi |
collection | PubMed |
description | For many years, anticoagulants have been used in the emergent treatment of patients with acute ischemic stroke. Anticoagulants are prescribed in an effort to prevent first or recurrent stroke, especially among patients with cardioembolism due to arterial fibrillation and large-artery atherosclerotic disease. Despite the widespread use, efficacy and safety of anticoagulants are controversial. Experts have given a broad spectrum of opinions. Surveys of practitioners have also demonstrated a lack of consensus on the use of anticoagulants for ischemic stroke. The uncertainty is due, in large part, to the lack of definitive clinical data. A review by the panel of the Stroke Council of the American Heart Association found no strong evidence for effectiveness of anticoagulants in treating acute ischemic stroke. Several clinical trials have suggested that utility of emergent anticoagulation has no significant effect in improving clinical outcomes for patients with acute ischemic stroke. In the present review, we have attempted to provide a framework for the emergent use of anticoagulants in acute ischemic stroke patients. |
format | Online Article Text |
id | pubmed-3526137 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35261372012-12-24 Anticoagulant therapy for ischemic stroke: A review of literature Shahpouri, Mohammad Mehdi Mousavi, Seyed Khorvash, Faribourz Mousavi, Seyed Morteza Hoseini, Tahereh J Res Med Sci Review Article For many years, anticoagulants have been used in the emergent treatment of patients with acute ischemic stroke. Anticoagulants are prescribed in an effort to prevent first or recurrent stroke, especially among patients with cardioembolism due to arterial fibrillation and large-artery atherosclerotic disease. Despite the widespread use, efficacy and safety of anticoagulants are controversial. Experts have given a broad spectrum of opinions. Surveys of practitioners have also demonstrated a lack of consensus on the use of anticoagulants for ischemic stroke. The uncertainty is due, in large part, to the lack of definitive clinical data. A review by the panel of the Stroke Council of the American Heart Association found no strong evidence for effectiveness of anticoagulants in treating acute ischemic stroke. Several clinical trials have suggested that utility of emergent anticoagulation has no significant effect in improving clinical outcomes for patients with acute ischemic stroke. In the present review, we have attempted to provide a framework for the emergent use of anticoagulants in acute ischemic stroke patients. Medknow Publications & Media Pvt Ltd 2012-04 /pmc/articles/PMC3526137/ /pubmed/23267405 Text en Copyright: © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Shahpouri, Mohammad Mehdi Mousavi, Seyed Khorvash, Faribourz Mousavi, Seyed Morteza Hoseini, Tahereh Anticoagulant therapy for ischemic stroke: A review of literature |
title | Anticoagulant therapy for ischemic stroke: A review of literature |
title_full | Anticoagulant therapy for ischemic stroke: A review of literature |
title_fullStr | Anticoagulant therapy for ischemic stroke: A review of literature |
title_full_unstemmed | Anticoagulant therapy for ischemic stroke: A review of literature |
title_short | Anticoagulant therapy for ischemic stroke: A review of literature |
title_sort | anticoagulant therapy for ischemic stroke: a review of literature |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526137/ https://www.ncbi.nlm.nih.gov/pubmed/23267405 |
work_keys_str_mv | AT shahpourimohammadmehdi anticoagulanttherapyforischemicstrokeareviewofliterature AT mousaviseyed anticoagulanttherapyforischemicstrokeareviewofliterature AT khorvashfaribourz anticoagulanttherapyforischemicstrokeareviewofliterature AT mousaviseyedmorteza anticoagulanttherapyforischemicstrokeareviewofliterature AT hoseinitahereh anticoagulanttherapyforischemicstrokeareviewofliterature |