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Universal heteroplasmy of human mitochondrial DNA

Mammalian cells contain thousands of copies of mitochondrial DNA (mtDNA). At birth, these are thought to be identical in most humans. Here, we use long read length ultra-deep resequencing-by-synthesis to interrogate regions of the mtDNA genome from related and unrelated individuals at unprecedented...

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Detalles Bibliográficos
Autores principales:	Payne, Brendan A.I., Wilson, Ian J., Yu-Wai-Man, Patrick, Coxhead, Jonathan, Deehan, David, Horvath, Rita, Taylor, Robert W., Samuels, David C., Santibanez-Koref, Mauro, Chinnery, Patrick F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526165/ https://www.ncbi.nlm.nih.gov/pubmed/23077218 http://dx.doi.org/10.1093/hmg/dds435

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