Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background

Telomere position effect (TPE) is the influence of telomeres on subtelomeric epigenetic marks and gene expression. Previous studies suggested that TPE depends on genetic background. As these analyses were performed on different chromosomes, cell types and species, it remains unclear whether TPE repr...

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Detalles Bibliográficos
Autores principales: Weuts, An, Voet, Thierry, Verbeeck, Jelle, Lambrechts, Nathalie, Wirix, Evelyne, Schoonjans, Luc, Danloy, Sophie, Marynen, Peter, Froyen, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526267/
https://www.ncbi.nlm.nih.gov/pubmed/23066103
http://dx.doi.org/10.1093/nar/gks926

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