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Pol β associated complex and base excision repair factors in mouse fibroblasts

During mammalian base excision repair (BER) of lesion-containing DNA, it is proposed that toxic strand-break intermediates generated throughout the pathway are sequestered and passed from one step to the next until repair is complete. This stepwise process is termed substrate channeling. A working m...

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Detalles Bibliográficos
Autores principales: Prasad, Rajendra, Williams, Jason G., Hou, Esther W., Wilson, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526277/
https://www.ncbi.nlm.nih.gov/pubmed/23042675
http://dx.doi.org/10.1093/nar/gks898