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Compression of next-generation sequencing reads aided by highly efficient de novo assembly

We present Quip, a lossless compression algorithm for next-generation sequencing data in the FASTQ and SAM/BAM formats. In addition to implementing reference-based compression, we have developed, to our knowledge, the first assembly-based compressor, using a novel de novo assembly algorithm. A proba...

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Detalles Bibliográficos
Autores principales: Jones, Daniel C., Ruzzo, Walter L., Peng, Xinxia, Katze, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526293/
https://www.ncbi.nlm.nih.gov/pubmed/22904078
http://dx.doi.org/10.1093/nar/gks754