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Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancy

Heterochromatin protein 1γ (HP1γ) is a chromatin protein involved in gene silencing. Herein, we show that HP1γ interacts with breast cancer type 1 susceptibility protein (BRCA1) and regulates BRCA1-mediated transcription via modulation of promoter occupancy and histone modification. We used several...

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Detalles Bibliográficos
Autores principales:	Choi, Jae Duk, Park, Mi Ae, Lee, Jong-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526311/ https://www.ncbi.nlm.nih.gov/pubmed/23074186 http://dx.doi.org/10.1093/nar/gks947

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