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Distinct requirements for T-bet in gut innate lymphoid cells
Interleukin (IL)-22–producing innate lymphoid cells (ILCs; ILC22) comprise a heterogeneous population of cells that are dependent on the transcription factor retinoid-related orphan γt (RORγt) and are critical for barrier function of the intestinal mucosa. A distinct ILC22 subset expresses the natur...
Autores principales: | Sciumé, Giuseppe, Hirahara, Kiyoshi, Takahashi, Hayato, Laurence, Arian, Villarino, Alejandro V., Singleton, Kentner L., Spencer, Sean P., Wilhelm, Christoph, Poholek, Amanda C., Vahedi, Golnaz, Kanno, Yuka, Belkaid, Yasmine, O'Shea, John J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526352/ https://www.ncbi.nlm.nih.gov/pubmed/23209316 http://dx.doi.org/10.1084/jem.20122097 |
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