Cargando…
Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling
The endogenous phospholipid lysophosphatidic acid (LPA) regulates fundamental cellular processes such as proliferation, survival, motility, and invasion implicated in homeostatic and pathological conditions. Hence, delineation of the full range of molecular mechanisms by which LPA exerts its broad e...
Autores principales: | Rai, Vivek, Touré, Fatouma, Chitayat, Seth, Pei, Renjun, Song, Fei, Li, Qing, Zhang, Jinghua, Rosario, Rosa, Ramasamy, Ravichandran, Chazin, Walter J., Schmidt, Ann Marie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526353/ https://www.ncbi.nlm.nih.gov/pubmed/23209312 http://dx.doi.org/10.1084/jem.20120873 |
Ejemplares similares
-
RAGE Modulates Hypoxia/Reoxygenation Injury in Adult Murine Cardiomyocytes via JNK and GSK-3β Signaling Pathways
por: Shang, Linshan, et al.
Publicado: (2010) -
Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction
por: Manigrasso, Michaele B., et al.
Publicado: (2016) -
Lysophosphatidic acid-RAGE axis promotes lung and mammary oncogenesis via protein kinase B and regulating tumor microenvironment
por: Ray, Rashmi, et al.
Publicado: (2020) -
RAGE signaling sustains inflammation and promotes tumor development
por: Gebhardt, Christoffer, et al.
Publicado: (2008) -
The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications
por: Ramasamy, Ravichandran, et al.
Publicado: (2022)