Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice

The inhibitory programmed death 1 (PD-1)–programmed death ligand 1 (PD-L1) pathway contributes to the functional down-regulation of T cell responses during persistent systemic and local virus infections. The blockade of PD-1–PD-L1–mediated inhibition is considered as a therapeutic approach to reinvi...

Descripción completa

Detalles Bibliográficos
Autores principales: Frebel, Helge, Nindl, Veronika, Schuepbach, Reto A., Braunschweiler, Thomas, Richter, Kirsten, Vogel, Johannes, Wagner, Carsten A., Loffing-Cueni, Dominique, Kurrer, Michael, Ludewig, Burkhard, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526355/
https://www.ncbi.nlm.nih.gov/pubmed/23230000
http://dx.doi.org/10.1084/jem.20121015

Ejemplares similares

Ejemplares similares