Cargando…

BCL6 positively regulates AID and germinal center gene expression via repression of miR-155

The BCL6 proto-oncogene encodes a transcriptional repressor that is required for germinal center (GC) formation and whose de-regulation is involved in lymphomagenesis. Although substantial evidence indicates that BCL6 exerts its function by repressing the transcription of hundreds of protein-coding...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basso, Katia, Schneider, Christof, Shen, Qiong, Holmes, Antony B., Setty, Manu, Leslie, Christina, Dalla-Favera, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526356/ https://www.ncbi.nlm.nih.gov/pubmed/23166356 http://dx.doi.org/10.1084/jem.20121387

Ejemplares similares

Tracking Immunoglobulin Repertoire and Transcriptomic Changes in Germinal Center B Cells by Single-Cell Analysis
por: Corinaldesi, Clarissa, et al.
Publicado: (2022)

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome
por: Holmes, Antony B., et al.
Publicado: (2020)

BCL6 Controls the Expression of the B7-1/CD80 Costimulatory Receptor in Germinal Center B Cells
por: Niu, Huifeng, et al.
Publicado: (2003)

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
por: Zhang, Jiyuan, et al.
Publicado: (2015)

KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells
por: Vlasevska, Sofija, et al.
Publicado: (2023)

MEF2B mutations lead to deregulated expression of the BCL6 oncogene in Diffuse Large B cell Lymphoma
por: Ying, Carol Y., et al.
Publicado: (2013)

c-MYC is required for germinal center selection and cyclic re-entry
por: Dominguez-Sola, David, et al.
Publicado: (2012)

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context
por: Margolin, Adam A, et al.
Publicado: (2006)

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers
por: Lefebvre, Celine, et al.
Publicado: (2010)

Repression of human activation induced cytidine deaminase by miR-93 and miR-155
por: Borchert, Glen M, et al.
Publicado: (2011)

A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
por: Mani, Kartik M, et al.
Publicado: (2008)

Biology of Germinal Center B Cells Relating to Lymphomagenesis
por: Basso, Katia
Publicado: (2021)

Targeting miR-155 to Treat Experimental Scleroderma
por: Yan, Qingran, et al.
Publicado: (2016)

DOF AFFECTING GERMINATION 2 is a positive regulator of light-mediated seed germination and is repressed by DOF AFFECTING GERMINATION 1
por: Santopolo, Silvia, et al.
Publicado: (2015)

Corrigendum: Targeting miR-155 to Treat Experimental Scleroderma
por: Yan, Qingran, et al.
Publicado: (2016)

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
por: Fabbri, Giulia, et al.
Publicado: (2013)

Bcl-XL and Bcl-2 repress a common pathway of cell death
Publicado: (1995)

Fractal-like Distributions over the Rational Numbers in High-throughput Biological and Clinical Data
por: Trifonov, Vladimir, et al.
Publicado: (2011)

MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples
por: Trifonov, Vladimir, et al.
Publicado: (2013)

Genome-wide Identification of Post-translational Modulators of Transcription Factor Activity in Human B-Cells
por: Wang, Kai, et al.
Publicado: (2009)

Protective Role of miR-34c in Hypoxia by Activating Autophagy through BCL2 Repression
por: Kim, Soyoung, et al.
Publicado: (2022)

Chronic simian immunodeficiency virus infection is associated with contrasting phenotypes of dysfunctional Bcl6(+) germinal center B cells or Bcl6(−)Bcl2(+) non‐germinal center B cells
por: Onabajo, Olusegun O., et al.
Publicado: (2018)

miR-155 in the Resolution of Atherosclerosis
por: Bruen, Robyn, et al.
Publicado: (2019)

Gene Expression Profiling of Hairy Cell Leukemia Reveals a Phenotype Related to Memory B Cells with Altered Expression of Chemokine and Adhesion Receptors
por: Basso, Katia, et al.
Publicado: (2004)

Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2
por: ZENG, QI, et al.
Publicado: (2016)

SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps
por: Setty, Manu, et al.
Publicado: (2015)

Hypermethylation of the miR-155 gene in the whole blood and decreased plasma level of miR-155 in rheumatoid arthritis
por: Kolarz, Bogdan, et al.
Publicado: (2020)

Deregulation of dicer and mir-155 expression in liposarcoma
por: Vincenzi, Bruno, et al.
Publicado: (2015)

MiR-155: An Important Regulator of Neuroinflammation
por: Zingale, Valeria Domenica, et al.
Publicado: (2021)

The Role of miR-155 in Antitumor Immunity
por: Kalkusova, Katerina, et al.
Publicado: (2022)

Helminth Excreted/Secreted Antigens Repress Expression of LPS-Induced Let-7i but Not miR-146a and miR-155 in Human Dendritic Cells
por: Terrazas, Luis I., et al.
Publicado: (2013)

Repressed induction of interferon-related microRNAs miR-146a and miR-155 in peripheral blood mononuclear cells infected with HCV genotype 4
por: El-Ekiaby, Nada, et al.
Publicado: (2012)

Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma
por: Slezak-Prochazka, Izabella, et al.
Publicado: (2015)

Association of Tag SNPs and Rare CNVs of the MIR155HG/miR-155 Gene with Epilepsy in the Chinese Han Population
por: Tao, Hua, et al.
Publicado: (2015)

Clinical significance of miR-155 expression in breast cancer and effects of miR-155 ASO on cell viability and apoptosis
por: ZHENG, SHU-RONG, et al.
Publicado: (2012)

Preparation of a miR-155-activating nucleic acid nanoflower to study the molecular mechanism of miR-155 in inflammation
por: Wang, Wenxin, et al.
Publicado: (2022)

Disruption of the Bcl6 Gene Results in an Impaired Germinal Center Formation
por: Fukuda, Tetsuya, et al.
Publicado: (1997)

Bcl-6 directly represses the gene program of the glycolysis pathway
por: Oestreich, Kenneth J., et al.
Publicado: (2014)

MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression
por: Lu, Zhan-Jun, et al.
Publicado: (2017)

Downregulation of Mir-31, Mir-155, and Mir-564 in Chronic Myeloid Leukemia Cells
por: Hershkovitz Rokah, Oshrat, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_djqnqbhs9sjr02d08rd1qt405h