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An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation

BACKGROUND: A proper balance between different T helper (Th) cell subsets is necessary for normal functioning of the adaptive immune system. Revealing key genes and pathways driving the differentiation to distinct Th cell lineages provides important insight into underlying molecular mechanisms and n...

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Detalles Bibliográficos
Autores principales:	Äijö, Tarmo, Edelman, Sanna M, Lönnberg, Tapio, Larjo, Antti, Kallionpää, Henna, Tuomela, Soile, Engström, Emilia, Lahesmaa, Riitta, Lähdesmäki, Harri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526425/ https://www.ncbi.nlm.nih.gov/pubmed/23110343 http://dx.doi.org/10.1186/1471-2164-13-572

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