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Reconstructing genome mixtures from partial adjacencies
Many cancer genome sequencing efforts are underway with the goal of identifying the somatic mutations that drive cancer progression. A major difficulty in these studies is that tumors are typically heterogeneous, with individual cells in a tumor having different complements of somatic mutations. How...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526445/ https://www.ncbi.nlm.nih.gov/pubmed/23282028 http://dx.doi.org/10.1186/1471-2105-13-S19-S9 |