Cargando…
Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway
BACKGROUND: Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as library design and post-screening bioinformatics may be effecting the data gene...
Autores principales: | Fisher, Katherine H, Wright, Victoria M, Taylor, Amy, Zeidler, Martin P, Brown, Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526451/ https://www.ncbi.nlm.nih.gov/pubmed/23006893 http://dx.doi.org/10.1186/1471-2164-13-506 |
Ejemplares similares
-
Identification of JAK/STAT pathway regulators—Insights from RNAi screens
por: Müller, Patrick, et al.
Publicado: (2008) -
The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013) -
Methotrexate Is a JAK/STAT Pathway Inhibitor
por: Thomas, Sally, et al.
Publicado: (2015) -
Mechanisms of JAK/STAT pathway negative regulation by the short coreceptor Eye Transformer/Latran
por: Fisher, Katherine H., et al.
Publicado: (2016) -
Localised JAK/STAT Pathway Activation Is Required for Drosophila Wing Hinge Development
por: Johnstone, Kirsty, et al.
Publicado: (2013)