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Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

BACKGROUND: Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as library design and post-screening bioinformatics may be effecting the data gene...

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Detalles Bibliográficos
Autores principales: Fisher, Katherine H, Wright, Victoria M, Taylor, Amy, Zeidler, Martin P, Brown, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526451/
https://www.ncbi.nlm.nih.gov/pubmed/23006893
http://dx.doi.org/10.1186/1471-2164-13-506

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